(313) PENILE PROSTHETIC PIONEER: F. BRANTLEY SCOTT

Abstract Introduction Dr. F. Brantley Scott (1930-1991) was a pioneer of prosthetic urology in the early 1970s, revolutionizing the treatment of erectile dysfunction (ED) and urinary incontinence. This abstract explores the life and groundbreaking contributions of Dr. Scott, emphasizing his development of the artificial urinary sphincter (AUS) and inflatable penile prosthesis (IPP). Objective To provide a comprehensive review of the history of Dr. F. Brantley Scott. Methods Extensive web-based research and historical accounts by those who knew him provided the primary source of information. Results Born in Pearsall, Texas in 1930, Dr. Scott embodied the larger-than-life Texan spirit with charm and brilliance, and he was often seen in his signature cowboy boots, massive belt buckle, and cowboy hat. His journey took him from an undergraduate at the University of Texas at Austin to Baylor College of Medicine where he completed his urology residency, ultimately rising to become a full professor at Baylor and chief of urology at the VA Hospital and St. Luke’s Episcopal Hospital in Houston. Dr. Scott’s devotion to teaching and mentorship fostered the development of eponymous implant luminaries Drs. William Furlow, John Mulcahy, and Steven Wilson. He popularized urodynamics for bladder function assessment and played a pivotal role in the development of the AUS. While tinkering with AUS hydraulics, he used a silicone elastomer from the US space program to develop the first IPP, initially known as the Scott prosthesis. Despite the prevailing belief in the psychological origins of impotence, he challenged the status quo and brought prosthetic urology into the limelight. While not the first to patent the IPP (credited to Dr. Barish Strauch), Dr. Scott’s collaboration with American Medical Systems (AMS) made the IPP a reality for patients. Dr. Scott’s patient selection process for IPP included comprehensive psychiatric evaluations and nocturnal penile tumescence measurements in sleep labs, revealing the connection between REM sleep and nocturnal erections. A true renaissance man, he was a pilot, author, artist, sculptor, rancher, musician, engineer, and entrepreneur. He retired in 1990 to pursue his passion for flying, but tragically lost his life during a test flight of a self-constructed plane near his Texas home in 1991. Conclusions Dr. F. Brantley Scott was a true visionary and pioneer of prosthetic urology. His groundbreaking work developing the AUS and IPP, combined with his larger-than-life Texan spirit, continue to influence urology, honoring his legacy as an innovative brilliant figure in the field. Disclosure Any of the authors act as a consultant, employee or shareholder of an industry for: Boston Scientific, Endo Pharmaceuticals and Halozyme Therapeutics.