Comparison of a compression for seven days or overnight after endovenous radiofrequency ablation of superficial vein: A randomized controlled trial

ObjectiveTo compare the efficacy of compression stockings worn for 7 days or overnight after EVRFA.MethodsA single-centre, prospective, non-inferiority randomised controlled trial. The study included patients with clinical class C2-C4 chronic venous disease who underwent endovenous radiofrequency ablation (EVRFA) at Chulabhorn Hospital between October 2021 and October 2023. Sixty patients were assigned to wear the overnight compression group (<i>n</i> = 30) or for the 7-day compression group (<i>n</i> = 30). The primary outcome was targeted vein obliteration at 12 weeks. The secondary outcome measures were the revised Venous Clinical Severity Score (r-VCSS), Aberdeen Varicose Veins Severity Score (AVSS), pain score, complications and patient satisfaction.ResultsAt 12 weeks, both groups had a 100% target vein occlusion rate. There was no statistically significant difference in the r-VCSS, AVSS, patient satisfaction score, complications or pain score at day 1, day 14 and 12-16 weeks after the procedure. Overnight compression improved r-VCSS significantly.ConclusionOvernight compression was non-inferior to compression for 7 days after EVRFA.