CXCR4-targeted sensitive magnetic particle imaging for abdominal aortic aneurysm early detection and prognosis evaluation by recognizing total inflammatory cells
CXCR4 marks immune cells and inflammatory vascular cells in AAA and is associated with AAA prognosis in a mouse model of AAA. CXCR4-targeting multimodal MPI/FLI provides a novel approach for AAA prognosis prediction and early detection.
Authors
- Genmao Cao (ORCID: https://orcid.org/0000-0003-2199-6903)
- Bo Jiang (ORCID: https://orcid.org/0000-0001-5327-621X)
- Xuezhen Xuan (ORCID: https://orcid.org/0000-0002-3980-5514)
- Shijie Xin (ORCID: https://orcid.org/0000-0001-6278-8794)
- Ruijing Zhang (ORCID: https://orcid.org/0000-0003-0697-2217)
- Hezeng Dong (ORCID: https://orcid.org/0000-0001-5018-8900)
- Jie Tian (ORCID: https://orcid.org/0000-0003-0498-0432)
- Hui Hui (ORCID: https://orcid.org/0000-0002-6732-4232)
- Yaling Li (ORCID: https://orcid.org/0000-0001-9136-4990)
- Xiaohua Jia
Institutions
- Shanxi Medical University (CN)
- Chinese Academy of Sciences (CN)
- Shuozhou Central Hospital (CN)
- Shandong Institute of Automation (CN)
- Second Hospital of Shanxi Medical University (CN)
- First Hospital of China Medical University (CN)
- China Medical University (CN)
Publication Details
- Journal
- Cardiovascular Research
- Published
- 2024-12-10
- DOI
- https://doi.org/10.1093/cvr/cvae255
- Citations
- 7
- Primary Topic
- Aortic aneurysm repair treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.93
Funders
- National Natural Science Foundation of China
- Beijing Municipal Natural Science Foundation