Disulfiram-Loaded Nanoparticles Inhibit Long-Term Proliferation on Preadipocytes
Our data demonstrated the biological interaction of PCL NPs with adipose cells in vitro. The selective cytotoxicity of DSF towards preadipocytes resulted in milder effects when it was delivered nanoencapsulated compared to the free drug. These results suggest promising pharmacological alternatives for DSF long-term delivery on adipose tissue.
Authors
- Jorge Benavides (ORCID: https://orcid.org/0000-0002-9579-483X)
- Héctor Chapoy‐Villanueva (ORCID: https://orcid.org/0000-0002-3992-314X)
- Marco Rito‐Palomares (ORCID: https://orcid.org/0000-0002-5321-1763)
- Karla Mayolo‐Deloisa (ORCID: https://orcid.org/0000-0002-2826-2518)
- Omar Lozano (ORCID: https://orcid.org/0000-0003-3156-5779)
- Eduardo Vázquez‐Garza (ORCID: https://orcid.org/0000-0001-7149-8334)
- Judith Bernal‐Ramírez (ORCID: https://orcid.org/0000-0003-1223-7366)
- Helen Yarimet Lorenzo-Anota (ORCID: https://orcid.org/0000-0001-9560-4357)
- José Gómez-Cantú
Institutions
- Tecnológico de Monterrey (MX)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2024-12-01
- DOI
- https://doi.org/10.2147/ijn.s467909
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00