Stealth-Engineered Albumin-Coated Nanoparticles for Targeted Therapy: Effective Drug Delivery and Tumor Suppression in Xenograft-Zebrafish Model
The study demonstrates that HSA-coated nanoparticles can be used as a therapeutic nanoplatform with a safe profile and enhanced bioavailability. The ability to decorate these nanostructures with specific targeting agents, such as anti-CD19 antibodies, opens up the potential for developing versatile therapeutic platforms that can be tailored to target various clinical conditions.
Authors
- Maria Cristina Grimaldi (ORCID: https://orcid.org/0000-0002-4646-0032)
- Michele Dal Bo (ORCID: https://orcid.org/0000-0001-8668-7621)
- Luca De Maso
- Paolo Macor (ORCID: https://orcid.org/0000-0003-3079-4019)
- Giuseppe Toffoli (ORCID: https://orcid.org/0000-0002-5323-4762)
- Daniele Sblattero (ORCID: https://orcid.org/0000-0003-4309-242X)
- Sara Bozzer (ORCID: https://orcid.org/0000-0002-0793-0118)
- Marcello Manfredi (ORCID: https://orcid.org/0000-0003-0632-5618)
Institutions
- Università degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT)
- University of Trieste (IT)
- Centro di Riferimento Oncologico (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2024-12-01
- DOI
- https://doi.org/10.2147/ijn.s476241
- Citations
- 15
- Primary Topic
- Nanoparticle-Based Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 2.60