Pleiotrophin Overexpression Reduces Adolescent Ethanol Consumption and Modulates Ethanol‐Induced Glial Responses and Changes in the Perineuronal Nets in the Mouse Hippocampus
PTN overexpression reduces adolescent ethanol consumption and influences ethanol-induced effects on hippocampal neurogenesis, glial responses, and PNN remodeling. These findings underscore the importance of PTN in modulating alcohol-induced neurotoxicity.
Authors
- Héctor Cañeque‐Rufo (ORCID: https://orcid.org/0000-0001-8000-560X)
- Beatriz Martín‐Fernández (ORCID: https://orcid.org/0000-0002-1904-6194)
- Gonzalo Herradón (ORCID: https://orcid.org/0000-0002-1578-3744)
- Alba García‐Guerra (ORCID: https://orcid.org/0009-0004-1157-9457)
- Milagros Galán‐Llario (ORCID: https://orcid.org/0000-0003-3231-7566)
- Teresa Fontán‐Baselga (ORCID: https://orcid.org/0000-0001-6259-8165)
- Esther Gramage (ORCID: https://orcid.org/0000-0002-5134-1273)
- María Rodríguez‐Zapata
Institutions
- Universidad San Pablo CEU (ES)
- Instituto de Salud Carlos III (ES)
- Federación Española de Enfermedades Raras (ES)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1111/cns.70159
- Citations
- 3
- Primary Topic
- Proteoglycans and glycosaminoglycans research
- Type
- article
- Field-Weighted Citation Impact
- 0.98
Funders
- Universidad San Pablo - CEU
- Plan Nacional sobre Drogas
- Instituto de Salud Carlos III