Changes in the pharmacokinetics of lurasidone in a pregnant woman with schizophrenia

Decreased serum lurasidone levels during pregnancy may increase the risk of symptom worsening in patients with schizophrenia. Hence, clinicians should be knowledgeable about the risk of decreased drug levels and the need for therapeutic monitoring and dosage adjustments during pregnancy to maintain treatment efficacy and maternal and fetal health.

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Publication Details

Journal
Psychiatry and Clinical Neurosciences Reports
Published
2024-12-01
DOI
https://doi.org/10.1002/pcn5.70043
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Changes in the pharmacokinetics of lurasidone in a pregnant woman with schizophrenia

Mihoko Kawai, Tadashi Ogawa, Ryosuke Aratake
Psychiatry and Clinical Neurosciences Reports
Schizophrenia research and treatment
article

Changes in the pharmacokinetics of lurasidone in a pregnant woman with schizophrenia

Mihoko Kawai, Tadashi Ogawa, Ryosuke Aratake
article en

Abstract

Decreased serum lurasidone levels during pregnancy may increase the risk of symptom worsening in patients with schizophrenia. Hence, clinicians should be knowledgeable about the risk of decreased drug levels and the need for therapeutic monitoring and dosage adjustments during pregnancy to maintain treatment efficacy and maternal and fetal health.

Psychiatry and Clinical Neurosciences ReportsVol. 3(4)
Aichi Medical University (JP)
Good health and well-being
Openalex Percentile: Top 70%
Schizophrenia research and treatment
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