Cluster of extensively drug-resistant Shigella sonnei carrying blaCTX-M-15 in Los Angeles, California, 2023 to 2024
We describe 3 cases of extensively drug-resistant Shigella sonnei infections among men who have sex with men in Los Angeles, CA. Using whole-genome sequencing, we determined that they are highly genetically related, exhibit similar antimicrobial resistomes, and appear to be distinct from other circulating strains. These cases highlight the rapid expansion of extensively drug-resistant Shigella in the United States and the urgent need for appropriate detection and management.
Authors
- J.R. Caldera (ORCID: https://orcid.org/0000-0003-0563-8815)
- Daniel Z. Uslan (ORCID: https://orcid.org/0000-0002-9800-3482)
- Shangxin Yang (ORCID: https://orcid.org/0000-0001-9991-1178)
- Bennett Shaw (ORCID: https://orcid.org/0000-0002-0180-6802)
Institutions
- University of California, Los Angeles (US)
- Quest Diagnostics (United States) (US)
Publication Details
- Journal
- American Journal of Infection Control
- Published
- 2024-12-10
- DOI
- https://doi.org/10.1016/j.ajic.2024.12.005
- Citations
- 3
- Primary Topic
- Escherichia coli research studies
- Type
- article
- Field-Weighted Citation Impact
- 1.85
Funders
- University of California, Los Angeles