Electrochemical synthesis of nitrosation compounds using CH<sub>3</sub>NO<sub>2</sub> as a nitroso reagent
An electrochemical synthesis of various nitroso organic compounds (NOCs) from secondary amines was developed under metal-free and oxidant-free conditions. This method used commercially available nitromethane as the nitrosation reagent to provide various NOCs in good to excellent yields. Furthermore, the valuable drug molecule form desloratadine can be prepared by this method easily.
Authors
- Qi Sun (ORCID: https://orcid.org/0000-0002-1438-635X)
- Rong Deng (ORCID: https://orcid.org/0000-0002-1452-8020)
- Zhenggen Zha (ORCID: https://orcid.org/0000-0002-5388-0115)
- Kai Li (ORCID: https://orcid.org/0000-0003-1948-4116)
- Zhiyong Wang (ORCID: https://orcid.org/0000-0002-3400-2851)
Institutions
- University of Science and Technology of China (CN)
- Hefei University of Technology (CN)
- Hefei National Center for Physical Sciences at Nanoscale (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2024-12-10
- DOI
- https://doi.org/10.1039/d4cc05521g
- Primary Topic
- Ammonia Synthesis and Nitrogen Reduction
- Type
- article
- Field-Weighted Citation Impact
- 0.00