Genomic Effects of Biomechanical Loading in Adolescent Human Growth Plate Cartilage: A Pilot Study
Our study provides the first-ever transcriptomic data of mechanical loading of human growth plate cartilage. These findings can potentially provide genetic targets for future investigations in physiological and pathological bone growth conditions.
Authors
- Nageswara Rao Boggavarapu (ORCID: https://orcid.org/0000-0002-8588-8445)
- Laila Sara Arroyo Mühr (ORCID: https://orcid.org/0000-0003-2498-5206)
- Tim Aeppli (ORCID: https://orcid.org/0000-0002-5499-4763)
- Lars Sävendahl (ORCID: https://orcid.org/0000-0003-1067-4976)
- Zhengpei Zhang
- Farasat Zaman (ORCID: https://orcid.org/0000-0002-1832-1051)
- Elena M. Gutierrez-Farewik (ORCID: https://orcid.org/0000-0001-5417-5939)
- Artem Kulachenko (ORCID: https://orcid.org/0000-0003-3611-2250)
- Tobia Nava (ORCID: https://orcid.org/0000-0003-0622-9298)
- Yunhan Zhao (ORCID: https://orcid.org/0000-0002-3002-8296)
- Ainhoa García‐Serrano (ORCID: https://orcid.org/0000-0003-1763-4053)
Institutions
- Karolinska University Hospital (SE)
- Karolinska Institutet (SE)
- KTH Royal Institute of Technology (SE)
Publication Details
- Journal
- Cartilage
- Published
- 2024-12-10
- DOI
- https://doi.org/10.1177/19476035241302954
- Citations
- 2
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Stiftelsen Promobilia
- Kungliga Tekniska Högskolan
- Vetenskapsrådet
- China Scholarship Council
- Barncancerfonden
- Marta and Gunnar V Philipson Foundation
- Sällskapet Barnavård