Crystal structure of luliconazole
The crystal structure of luliconazole {LCZ; C<sub>14</sub>H<sub>9</sub>Cl<sub>2</sub>N<sub>3</sub>S<sub>2</sub>; systematic name: (<i>E</i>)-[(4<i>R</i>)-4-(2,4-di-chloro-phen-yl)-1,3-di-thio-lan-2-yl-idene](1<i>H</i>-imidazol-1-yl)aceto-nitrile} is reported. In the mol-ecule of the title compound, the di-thiol-ane ring adopts an envelope conformation, while the di-chloro-phenyl ring exhibits disorder. In the crystal packing of luliconazole, only two inter-molecular C-H⋯N hydrogen bonds are observed. Hirshfeld surface analysis reveals that the most dominant contacts are H⋯N/N⋯H, H⋯Cl/Cl⋯H, H⋯H and C⋯H/H⋯C.
Authors
- Lilianna Chęcińska (ORCID: https://orcid.org/0000-0002-3546-920X)
- Anna Ben
Institutions
- University of Łódź (PL)
- Exact Sciences (United States) (US)
Publication Details
- Journal
- Acta Crystallographica Section E Crystallographic Communications
- Published
- 2024-12-10
- DOI
- https://doi.org/10.1107/s2056989024011812
- Primary Topic
- Veterinary medicine and infectious diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Uniwersytet Łódzki