DELIVERING MDD TREATMENT WITH THE H7 DEEP TMS COIL: 120% OF THE HAND MT VERSUS 100% OF THE FOOT MT
1800 pulses) are delivered continuously over 120 seconds to the right dorsolateral prefrontal cortex (RDLPFC) is administered first, followed by iTBS in which (1800 pulses) are delivered in 2 second bursts, repeated every 10 seconds for 570 seconds to the left dorsolateral prefrontal cortex (LDLPFC) with using beam method for target localization.Stimulation was at 90% MT with an intersession interval of fifty minutes.The following scales were applied at the baseline and at the end of each day of five treatment days: Montgomery and Asberg Depression Rating Scale (MADRS), Beck Depression Inventory, Columbia Suicide Severity Rating Scale (C-SSRS), and Young Mania Rating Scale (YMRS).Results: All seven patients were completely improved regarding both suicidality and depression after the 5-day course without emerging of hypomania.Conclusions: Bilateral accelerated theta burst stimulation shows promise as a highly effective treatment option for suicidality in patients with bipolar depression.Further trials are needed to confirm results.
Authors
- Maor Yeshua (ORCID: https://orcid.org/0000-0002-3463-5624)
- Shmuel Hess
- Colleen A. Hanlon (ORCID: https://orcid.org/0000-0002-3151-0279)
- Yuri Burnishev
- Dror Weiss
- Elisha Moses (ORCID: https://orcid.org/0000-0002-0455-1323)
- Ami Eisen
- Gaby S. Pell
- Yiftach Roth
Institutions
- Ben-Gurion University of the Negev (IL)
- Geha Mental Health Center (IL)
- Lev Hasharon Hospital (IL)
- Weizmann Institute of Science (IL)
Publication Details
- Journal
- Transcranial magnetic stimulation .
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1016/j.transm.2024.100015
- Primary Topic
- Reconstructive Surgery and Microvascular Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00