Identification of Candidate Hub Genes and Drug Targets for Cholangiocarcinoma via Juhua (Chrysanthemum Morifolium) Bioactivity and Molecular Docking: A Bioinformatics Approach

Our multi-omic analysis provides new insight into molecular underpinnings of CHOL and identifies candidate disease drivers, signaling pathways and herbal targets for further validation. This systematic approach established a framework for illuminating causal links between genetics, molecular mechanisms and disease pathogenesis, with potential to accelerate drug and biomarker development for CHOL.

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Publication Details

Journal
Cancer Management and Research
Published
2024-12-01
DOI
https://doi.org/10.2147/cmar.s478907
Primary Topic
Cancer Mechanisms and Therapy
Type
article
Field-Weighted Citation Impact
0.00
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article

Identification of Candidate Hub Genes and Drug Targets for Cholangiocarcinoma via Juhua (Chrysanthemum Morifolium) Bioactivity and Molecular Docking: A Bioinformatics Approach

Zheng Lü, Yang Song, Shuo Zhou, Wanliang Sun
Cancer Management and Research
Cancer Mechanisms and Therapy
article

Identification of Candidate Hub Genes and Drug Targets for Cholangiocarcinoma via Juhua (Chrysanthemum Morifolium) Bioactivity and Molecular Docking: A Bioinformatics Approach

Zheng Lü, Yang Song, Shuo Zhou, Wanliang Sun
article en

Abstract

Our multi-omic analysis provides new insight into molecular underpinnings of CHOL and identifies candidate disease drivers, signaling pathways and herbal targets for further validation. This systematic approach established a framework for illuminating causal links between genetics, molecular mechanisms and disease pathogenesis, with potential to accelerate drug and biomarker development for CHOL.

Cancer Management and ResearchVol. Volume 16
First Affiliated Hospital of Bengbu Medical College (CN)
Zero hunger
Openalex Percentile: Top 63%
Cancer Mechanisms and Therapy
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