Identification of Candidate Hub Genes and Drug Targets for Cholangiocarcinoma via Juhua (Chrysanthemum Morifolium) Bioactivity and Molecular Docking: A Bioinformatics Approach
Our multi-omic analysis provides new insight into molecular underpinnings of CHOL and identifies candidate disease drivers, signaling pathways and herbal targets for further validation. This systematic approach established a framework for illuminating causal links between genetics, molecular mechanisms and disease pathogenesis, with potential to accelerate drug and biomarker development for CHOL.
Authors
- Zheng Lü (ORCID: https://orcid.org/0000-0002-9090-0875)
- Yang Song (ORCID: https://orcid.org/0000-0002-6248-8086)
- Shuo Zhou (ORCID: https://orcid.org/0000-0003-2795-6865)
- Wanliang Sun
Institutions
- First Affiliated Hospital of Bengbu Medical College (CN)
Publication Details
- Journal
- Cancer Management and Research
- Published
- 2024-12-01
- DOI
- https://doi.org/10.2147/cmar.s478907
- Primary Topic
- Cancer Mechanisms and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00