Conventional as well as Microwave Assisted Synthesis Characterization and Antimicrobial Studies of Some New Derivatives of -5-[2'-Marcapto-1-Methylene)-(1', 3’, 4’-Thiadiazoles)] - 1, 2, 3-Benzotriazoles

As a part of systematic investigation of conventional as well as microwave assisted synthesis and antimicrobial activity, of several new 5-[(2'-N-sub.arylidene hydrazinothioacetyl)-1-(methylene)-1',3',4'-thiadia-zoles)]-1,2,3-benzotriazoles 3a and 5-[(2'-sub.aryl-3'"-chloro-2'"-oxo-azetidine)-1"-(iminothioacetyl)-1-(methylene-1',3',4'-thiadiazole)]-1,2,3-benzotriazole1 as the starting material. All the synthesized products were evaluated for their antibacterial activity against Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae and Bacillus substilis and antifungal activity against Aspergillus Niger, Aspergillus flavus, Fusarium oxisporum and Trichoderma viride. The structures of all the synthesized compounds have been determined by spectral and chemical methods.

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Publication Details

Journal
International Journal of Drug Design and Discovery
Published
2024-11-28
DOI
https://doi.org/10.37285/ijddd.1.4.2
Primary Topic
Synthesis and biological activity
Type
article
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article

Conventional as well as Microwave Assisted Synthesis Characterization and Antimicrobial Studies of Some New Derivatives of -5-[2'-Marcapto-1-Methylene)-(1', 3’, 4’-Thiadiazoles)] - 1, 2, 3-Benzotriazoles

Jyoti Sen, Deepak Shukla, A Jain
International Journal of Drug Design and Discovery
Synthesis and biological activity
article

Conventional as well as Microwave Assisted Synthesis Characterization and Antimicrobial Studies of Some New Derivatives of -5-[2'-Marcapto-1-Methylene)-(1', 3’, 4’-Thiadiazoles)] - 1, 2, 3-Benzotriazoles

Jyoti Sen, Deepak Shukla, A Jain
article en

Abstract

As a part of systematic investigation of conventional as well as microwave assisted synthesis and antimicrobial activity, of several new 5-[(2'-N-sub.arylidene hydrazinothioacetyl)-1-(methylene)-1',3',4'-thiadia-zoles)]-1,2,3-benzotriazoles 3a and 5-[(2'-sub.aryl-3'"-chloro-2'"-oxo-azetidine)-1"-(iminothioacetyl)-1-(methylene-1',3',4'-thiadiazole)]-1,2,3-benzotriazole1 as the starting material. All the synthesized products were evaluated for their antibacterial activity against Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae and Bacillus substilis and antifungal activity against Aspergillus Niger, Aspergillus flavus, Fusarium oxisporum and Trichoderma viride. The structures of all the synthesized compounds have been determined by spectral and chemical methods.

International Journal of Drug Design and DiscoveryVol. 1(4)
Dr. Hari Singh Gour University (IN)
Openalex Percentile: Top 83%
Synthesis and biological activity
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