Conventional as well as Microwave Assisted Synthesis Characterization and Antimicrobial Studies of Some New Derivatives of -5-[2'-Marcapto-1-Methylene)-(1', 3’, 4’-Thiadiazoles)] - 1, 2, 3-Benzotriazoles
As a part of systematic investigation of conventional as well as microwave assisted synthesis and antimicrobial activity, of several new 5-[(2'-N-sub.arylidene hydrazinothioacetyl)-1-(methylene)-1',3',4'-thiadia-zoles)]-1,2,3-benzotriazoles 3a and 5-[(2'-sub.aryl-3'"-chloro-2'"-oxo-azetidine)-1"-(iminothioacetyl)-1-(methylene-1',3',4'-thiadiazole)]-1,2,3-benzotriazole1 as the starting material. All the synthesized products were evaluated for their antibacterial activity against Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae and Bacillus substilis and antifungal activity against Aspergillus Niger, Aspergillus flavus, Fusarium oxisporum and Trichoderma viride. The structures of all the synthesized compounds have been determined by spectral and chemical methods.
Authors
- Jyoti Sen
- Deepak Shukla (ORCID: https://orcid.org/0000-0002-3039-6953)
- A Jain
Institutions
- Dr. Hari Singh Gour University (IN)
Publication Details
- Journal
- International Journal of Drug Design and Discovery
- Published
- 2024-11-28
- DOI
- https://doi.org/10.37285/ijddd.1.4.2
- Primary Topic
- Synthesis and biological activity
- Type
- article
- Field-Weighted Citation Impact
- 0.00