Pelvic Disorders in Patients with Multiple Sclerosis in the Presence of Comorbidity

The prevalence and features of pelvic disorders in patients with multiple sclerosis with comorbidity were investigated. In total, 216 patients with various forms of the disease were examined. Clinical and demographic data, paraclinical characteristics, significance of nervous system dysfunction and disability, degree of pelvic dysfunction, severity of pain, severity of fatigue, severity of depression, severity of cognitive disorders, indicators of quality of life were analyzed. During the clinical examination, the body mass index, the presence or absence of comorbid diseases and their duration were clinically determined, laboratory, instrumental studies and examinations by other specialists were used (ophthalmologist, therapist, cardiologist, rheumatologist, urologist, dentist). When conducting a study of patients with multiple sclerosis of the general sample, symptoms associated with a violation of pyramidal functions were registered in 191 patients (88.4%), symptoms caused by a violation of cerebellar functions – in 178 patients (82.4%), symptoms caused by a violation of the functions of the trunk of the brain and cranial nerves – in 161 patients (74.5%), symptoms associated with impaired sensitivity functions – in 169 patients (78.2%), symptoms due to pelvic disorders – in 187 patients (87.0%), symptoms, caused by impaired visual functions – in 116 patients (53.7%), symptoms associated with impaired cerebral (mental) functions – in 184 patients (85.2%). Pelvic organ dysfunction in patients with multiple sclerosis were most clearly correlated with the duration of the disease, level of disability, female sex, level of fatigue and indicators of quality of life. In the group of patients with multiple sclerosis with comorbid pathology, there is a significant prevalence of symptoms of pelvic organ dysfunction and combined forms of pelvic organ dysfuncion.