Virological and serological outcomes in people with HIV-HBV coinfection who had discontinued tenofovir-containing antiretroviral therapy: Results from a prospective cohort study
This proof-of-concept study shows that selected people with HIV-HBV coinfection may not lose virologic control of HBV when off tenofovir. HBV virologic activity while off tenofovir may be more closely associated with uncontrolled HIV infection and positive HBeAg serology.
Authors
- Caroline Lascoux‐Combe (ORCID: https://orcid.org/0000-0003-2049-8048)
- Audrey Gabassi (ORCID: https://orcid.org/0009-0002-8478-9506)
- Constance Delaugerre (ORCID: https://orcid.org/0000-0001-6081-7993)
- Anders C. Boyd (ORCID: https://orcid.org/0000-0001-9512-8928)
- Sarah Maylin (ORCID: https://orcid.org/0000-0002-0991-4381)
- Patrick Miailhes (ORCID: https://orcid.org/0000-0002-7979-3829)
- Julie Bottero (ORCID: https://orcid.org/0000-0002-0294-5628)
- Emily P. Hyle (ORCID: https://orcid.org/0000-0001-8721-106X)
- Amir M. Mohareb
- Karine Lacombe (ORCID: https://orcid.org/0000-0001-8772-9029)
- Julie Chas (ORCID: https://orcid.org/0000-0002-1001-9229)
- Hayette Rougier (ORCID: https://orcid.org/0000-0002-3925-2921)
Institutions
- University of London Institute in Paris (FR)
- Harvard University (US)
- Inserm (FR)
- École des Hautes Études en Santé Publique (FR)
- Université Paris Cité (FR)
- AIDS United (US)
- Sorbonne Université (FR)
- Massachusetts General Hospital (US)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hôpital Saint-Antoine (FR)
- Hôpital d'Enfants (FR)
- Institut de Médecine et d'Epidémiologie Africaines (FR)
- Stichting HIV Monitoring (NL)
- Institut Pierre Louis d‘Épidémiologie et de Santé Publique (FR)
- Hôpital Saint-Louis (FR)
- Bicêtre Hospital (FR)
- Hôpital Tenon (FR)
- Institut de recherche Saint-Louis (FR)
- University of Amsterdam (NL)
Publication Details
- Journal
- Journal of Virus Eradication
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1016/j.jve.2024.100574
- Citations
- 3
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Massachusetts General Hospital
- Division of Intramural Research, National Institute of Allergy and Infectious Diseases
- Harvard University
- Harvard University Center for AIDS Research
- Sidaction
- Agence Nationale de Recherches sur le Sida et les Hépatites Virales
- National Institutes of Health
- Center for AIDS Research, University of Washington
- National Institute of Allergy and Infectious Diseases