Predictive validity of interleukin 6 (IL-6) for the mortality in critically ill COVID-19 patients with the B.1.617.2 (Delta) variant in Vietnam: a single-centre, cross-sectional study

This study focused on a highly selected cohort of critically ill COVID-19 patients with a high IL-6 level and mortality rate. Despite the poor discriminatory value of admission IL-6 levels, the rate of change in IL-6 proved valuable in predicting mortality. To identify critically ill COVID-19 patients with the highest risk for mortality, monitoring the serial serum IL-6 measurements and observing the rate of change in serum IL-6 levels over time are needed.

Authors

Institutions

Publication Details

Journal
BMJ Open
Published
2024-12-01
DOI
https://doi.org/10.1136/bmjopen-2024-085971
Citations
5
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.93
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Predictive validity of interleukin 6 (IL-6) for the mortality in critically ill COVID-19 patients with the B.1.617.2 (Delta) variant in Vietnam: a single-centre, cross-sectional study

Nhung Thi Hong Huynh, Dao Xuan Co, Thom Thi Vu, Quynh Thi Pham et al.
5 citations
BMJ Open
Sepsis Diagnosis and Treatment
1.93
article

Predictive validity of interleukin 6 (IL-6) for the mortality in critically ill COVID-19 patients with the B.1.617.2 (Delta) variant in Vietnam: a single-centre, cross-sectional study

Nhung Thi Hong Huynh, Dao Xuan Co, Thom Thi Vu, Quynh Thi Pham, Nguyen Duc Vinh, Chi Van Nguyen, Cuong Duy, Khoi Hong Vo, Nhung Hong Khuat, Nguyen Trung Nguyen, Tuan Quoc Dang, My Ha Nguyen, Dung Van Nguyen, Thai Quoc Nguyen, Dung Thi Pham, Tan Cong Nguyen, Do Ngoc Son, Thach The Phạm, Hung Duc Ngo, Vuong Minh Nong, Giap Van Vu, Thuan Quang Le, Viet Khoi Nguyen, Chinh Quoc Luong, Duy Cuong Nguyen, Dung T. Nguyen, Dat Nguyen, Phuong Minh Nguyen, Dat Tien Hoang, Tan An Dang, Dung Tuan Dang, Anh Diep Nguyen, Duong Dai Cao, Nga Thu Phan, Dung Pham
article en
5 citations

Abstract

This study focused on a highly selected cohort of critically ill COVID-19 patients with a high IL-6 level and mortality rate. Despite the poor discriminatory value of admission IL-6 levels, the rate of change in IL-6 proved valuable in predicting mortality. To identify critically ill COVID-19 patients with the highest risk for mortality, monitoring the serial serum IL-6 measurements and observing the rate of change in serum IL-6 levels over time are needed.

BMJ OpenVol. 14(12)
Vietnam National University, Hanoi (VN), Hanoi Medical University (VN), University of Medicine and Pharmacy at Ho Chi Minh City (VN), Thai Binh University of Medicine and Pharmacy (VN), Khanh Hoa General Hospital (VN), Bạch Mai Hospital (VN), Viet Duc Hospital (VN)
Openalex Percentile: Top 13%
Sepsis Diagnosis and Treatment
1.93
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.