Efficacy of a fixed low dose of radioactive iodine in the treatment of Graves' disease in Sub-Saharan Africa.

The use of a low fixed/empiric radioiodine activity for hyperthyroidism due to Graves' disease performed well in our setting with a nearly 90% response rate achieved after a single dose of 10mCi. Justification for higher activity should be specified, and this method of determining the optimal dose of RAI therapy may be beneficial in resource constrained settings with high patient volumes.

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Publication Details

Journal
PubMed
Published
2024-12-29
DOI
https://doi.org/10.1967/s002449912751
Primary Topic
Radiopharmaceutical Chemistry and Applications
Type
article
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article

Efficacy of a fixed low dose of radioactive iodine in the treatment of Graves' disease in Sub-Saharan Africa.

Lerato Gabela, Nontobeko Ndlovu, Nozipho Nyakale, Venesen Pillay et al.
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PubMed
Radiopharmaceutical Chemistry and Applications
article

Efficacy of a fixed low dose of radioactive iodine in the treatment of Graves' disease in Sub-Saharan Africa.

Lerato Gabela, Nontobeko Ndlovu, Nozipho Nyakale, Venesen Pillay, Bawinile Hadebe, Mariza Vorster, Lerwine Harry, Thembelihle Nxasana, Sphelele Masikane, Maryam Patel, Thokozani Mkhiz
article en

Abstract

The use of a low fixed/empiric radioiodine activity for hyperthyroidism due to Graves' disease performed well in our setting with a nearly 90% response rate achieved after a single dose of 10mCi. Justification for higher activity should be specified, and this method of determining the optimal dose of RAI therapy may be beneficial in resource constrained settings with high patient volumes.

PubMedVol. 27(3)
University of KwaZulu-Natal (ZA)
Openalex Percentile: Top 61%
Radiopharmaceutical Chemistry and Applications
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