Investigation of the Effects of Blocking Potassium Channels With 4‐Aminopyridine on Paclitaxel Activity in Breast Cancer Cell Lines
Biophysical parameters like the transmembrane potential and ion fluxes have been defined in cancer progression which can provide new aspects for cancer treatments. This study shows that the combination of 4-AP with PTX is a promising alternative the mechanism of which needs further investigation considering the results obtained for Ca<sup>2+</sup>, K<sup>+</sup>, and membrane potential.
Authors
- Günseli Ayşe İnhan-Garip (ORCID: https://orcid.org/0000-0002-8182-3433)
- Esra Münire Cüce-Aydoğmuş (ORCID: https://orcid.org/0000-0002-8143-3574)
Institutions
- Maltepe University (TR)
- Marmara University (TR)
Publication Details
- Journal
- Cancer Reports
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/cnr2.70072
- Citations
- 2
- Primary Topic
- Ion channel regulation and function
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- Marmara Üniversitesi