Evaluation of Correlation Between the some physiolocigl and biochemical parameters with incretin hormones in patients with Type 2 Diabetes in AL-Najaf Government

tudy evaluated the level of GLP-1, GIP hormones and some biochemical parameters in patients with type 2 diabetes compared to healthy individuals and determined the relationship between them. The study included examination on (83) of both gender, 62 of them were type 2 diabetes patients (30 male and 32 female) who were receiving care at the (Diabetes –and Endocrine clinic at Al-sader educational Hospital in Najaf province) and remaining were healthy control they were divided into (8) male, (13) females and the study continued from 12-12 -2022 until 1-5 -2023. All samples included in the current study (patients and healthy people) underwent blood tests (CBC, N/L). As well as the biochemical and hormonal indicators included (TC, TG, LDL, HDL, VLDL, GIP, GLP-1). The finding of the present study indicated an insignificant rise in white blood cells, platelet count, and N/L count ratio, and a decrease in the average platelet volume, red blood cell count, and hemoglobin in the patient group compared with the control group. As for fat levels a significant increase in most types of fats was noted in the patient group in comparison to the control group, the findings of the present study indicate a significant reduction in concentration levels of hormones GLP-1 and GIP in diabetic patients compared to the control group. Regarding the correlations between criteria Physiological blood White blood cells , red blood cells and platelet count, A positive correlation was found between them and the hormone (GLP-1)