Stability Assessment of Methadone Hydrochloride Oral Solution for Dispensing in Drug Addiction Centers: A Physicochemical and Microbiological Study.
The 0.5% methadone solution showed chemical, physical, and microbiological stability for 60 days after preparation. These results have allowed extending the expiration date of the preparation and optimizing the dispensing circuit of methadone to Drug Dependency Centers.
Authors
- Marta Saura (ORCID: https://orcid.org/0000-0002-3977-6581)
- P Selvi-Sabater (ORCID: https://orcid.org/0000-0001-7695-3391)
- Marina Pascual
- Carmen Nieves Pérez Sánchez (ORCID: https://orcid.org/0000-0002-5217-4331)
- Elena Urbieta Sanz
- Ma Pilar Sánchez Piñera
Institutions
- Regional Health (US)
- Hospital Reina Sofía de Murcia (ES)
- Servicio Murciano de Salud (ES)
- Universidad de Murcia (ES)
Publication Details
- Journal
- PubMed
- Published
- 2024-12-06
- Primary Topic
- Analytical Methods in Pharmaceuticals
- Type
- article
- Field-Weighted Citation Impact
- 0.00