Exploring cytokine outputs for ex vivo diagnostics in drug reaction with eosinophilia and systemic symptoms (DRESS)
In patients where the early response has suggested a TH2 response such as DRESS, IL-4 and IL-5 cytokine outputs could present an investigational advantage, including when IFN-γ is negative. In the future, larger prospective studies are required to understand the role of varied cytokine outputs in T-cell-mediated hypersensitivities.
Authors
- Michelle Goh (ORCID: https://orcid.org/0000-0001-8063-8482)
- Jason A. Trubiano (ORCID: https://orcid.org/0000-0002-5111-6367)
- Effie Mouhtouris (ORCID: https://orcid.org/0000-0003-3491-2633)
- Fiona James (ORCID: https://orcid.org/0000-0003-0469-5666)
- Elizabeth Jane Phillips (ORCID: https://orcid.org/0000-0002-7623-3383)
- Ana Maria Copaescu (ORCID: https://orcid.org/0000-0002-9183-5032)
Institutions
- The University of Melbourne (AU)
- Murdoch University (AU)
- McGill University Health Centre (CA)
- St Vincent's Hospital Melbourne (AU)
- Peter Doherty Institute (AU)
- Alfred Health (AU)
- Austin Health (AU)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- World Allergy Organization Journal
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1016/j.waojou.2024.101002
- Citations
- 4
- Primary Topic
- Drug-Induced Adverse Reactions
- Type
- article
- Field-Weighted Citation Impact
- 1.79
Funders
- Austin Medical Research Foundation
- Medical Research Council
- National Health and Medical Research Council