Development and validation of a prognostic and drug sensitivity model for gastric cancer utilizing telomere-related genes
The study establishes suggestive relationships between four TRGs (LRRN1, SNCG, GAMT, and PDE1B) and the prognosis of GC. The comprehensive characterization of the TRG model reveals their possible roles in the prognosis, TIME, and drug sensitivity in GC.
Authors
- Daxin Chen (ORCID: https://orcid.org/0000-0001-7028-0704)
- Zhongyu Lu (ORCID: https://orcid.org/0009-0000-6813-7650)
- Zhongguo Li (ORCID: https://orcid.org/0000-0002-0573-4391)
- Xiaoxiao Li (ORCID: https://orcid.org/0000-0002-1385-5898)
- Xiaoxuan Wang (ORCID: https://orcid.org/0000-0001-7028-0667)
- Dongsheng Chen (ORCID: https://orcid.org/0000-0003-2400-0315)
- Yingxue Qi
- Yaqin Liu (ORCID: https://orcid.org/0000-0003-0019-9403)
- Fuxiang Yu (ORCID: https://orcid.org/0000-0003-4784-7113)
- Yaoqiang Wu
Institutions
- Wuhan Wudong Hospital (CN)
- Simcere Pharmaceutical (China) (CN)
- First Hospital of China Medical University (CN)
- Jinzhou Medical University (CN)
- China Medical University (CN)
- Eastern Liaoning University (CN)
Publication Details
- Journal
- Translational Oncology
- Published
- 2024-12-07
- DOI
- https://doi.org/10.1016/j.tranon.2024.102232
- Citations
- 4
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 1.31
Funders
- Natural Science Foundation of Liaoning Province