Exploring the Causal Relationship Between Inflammatory Cytokines and MRI‐Derived Brain Iron: A Mendelian Randomization Study
Our findings suggest a causal association between circulating inflammatory cytokines and brain iron deposition across various brain regions. This provides new insights into the immunopathogenesis of neurodegenerative diseases and potential preventive strategies targeting iron metabolism.
Authors
- Zhongbiao Jiang (ORCID: https://orcid.org/0009-0008-1741-8557)
- Dan Peng
- Wantong Xu
- Zhounan Wu
- Xuemei Wang (ORCID: https://orcid.org/0009-0000-7909-3171)
Institutions
- Central South University (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/brb3.70181
- Citations
- 2
- Primary Topic
- Iron Metabolism and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.91
Funders
- Natural Science Foundation of Hunan Province