Intestinal Dysbiosis and its Relationship with Autistic Spectrum Disorder in Kids

This systematic review analyses the possible association between the intestinal microbiota and Autism Spectrum Disorder (ASD). It delves into the involvement of the gut-brain-microbiota axis and other factors implicated in maintaining a healthy microbiota. The brain and the gastrointestinal tract (GIT) exchange information with a bidirectional pathway. Multiple neurodegenerative diseases such as Parkinson's and Alzheimer's are linked to dysbiosis, an alteration in the gut microbiota. However, there is evidence supporting the association between dysbiosis and the neurodevelopment of ASD. Therefore, current treatment options focus on patient nutrition and diet. In this review, the best evidence regarding the effect of nutrition on children with ASD.