Folate and vitamin B12 supplementation in patients with schizophrenia and low serum folate level: A 24-week randomized, double-blind, placebo-controlled study
Our finding suggested that the extent of increased folate levels did not exert a notable impact on the changes of psychotic symptoms severity or cognitive function in our patients. It may also due to the relatively stable condition in our recruited patients, so supplementation of folate cannot show its effectiveness. Whether folate can improve psychopathology in moderate to severe patients with schizophrenia should be evaluated with a larger sample size in the future.
Authors
- Yi-Hang Chiu
- Chun-Hsin Chen (ORCID: https://orcid.org/0000-0002-1776-8556)
- Ming‐Chyi Huang (ORCID: https://orcid.org/0000-0001-9751-9834)
- Yu‐Han Chang (ORCID: https://orcid.org/0009-0009-8536-3954)
- Chih‐Chiang Chiu (ORCID: https://orcid.org/0000-0002-5475-230X)
- Po‐Yu Chen (ORCID: https://orcid.org/0000-0002-2926-1031)
- Mong‐Liang Lu (ORCID: https://orcid.org/0000-0002-8281-8193)
- Chin-Hao Chang
Institutions
- Taipei Medical University Hospital (TW)
- Taipei City Hospital (TW)
- National Taiwan University Hospital (TW)
- Wan Fang Hospital (TW)
- Taipei Medical University (TW)
Publication Details
- Journal
- Journal of the Formosan Medical Association
- Published
- 2024-12-06
- DOI
- https://doi.org/10.1016/j.jfma.2024.11.019
- Citations
- 2
- Primary Topic
- Folate and B Vitamins Research
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Ministry of Science and Technology, Taiwan