Tyrosine oxime derivatives from the fruiting bodies of basidiomycete <i>Serpula dendrocalami</i>
Three undescribed <i>O</i>-prenyl-tyrosine oxime derivatives, serpulanines D-F (<b>1-3</b>), were isolated from natural fruiting bodies of the basidiomycete <i>Serpula dendrocalami</i> together with serpulanine C (<b>4</b>), and other known compounds (<b>5-8</b>). The structures were elucidated based on NMR spectroscopic and mass spectrometry data. Compounds <b>1</b>-<b>3</b> were screened for their antibacterial activities against <i>Staphylococcus aureus</i> (MRSA and MSSA) and <i>Bacillus cereus</i> using the agar well diffusion method at 1 mg/mL. All of them were inactive in the antibacterial activity assays.
Authors
- Kusavadee Sangdee (ORCID: https://orcid.org/0000-0003-0481-8267)
- Masahiko Isaka (ORCID: https://orcid.org/0000-0002-9229-3394)
- Prapairat Seephonkai (ORCID: https://orcid.org/0000-0003-2451-9029)
- Ruchilak Rattarom (ORCID: https://orcid.org/0000-0002-3477-0121)
- Aphidech Sangdee (ORCID: https://orcid.org/0000-0003-4401-8985)
- Jiraporn Panchompoo
- Chiraphat Takpho
- Khwanyuruan Naksuwankul
- Khemika Singmahan
Institutions
- Mahasarakham University (TH)
- National Science and Technology Development Agency (TH)
- National Center for Genetic Engineering and Biotechnology (TH)
Publication Details
- Journal
- Natural Product Research
- Published
- 2024-12-06
- DOI
- https://doi.org/10.1080/14786419.2024.2438267
- Primary Topic
- Microbial Natural Products and Biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Council of Thailand