Preoperative Anxiety’s Impact on the Median Effective Dose of Esketamine for Alleviating Propofol Injection Pain in Patients Undergoing Painless abortion: A Randomized, Double-Blind, Controlled Trial
Preoperative anxiety significantly increases the ED<sub>50</sub> of esketamine required to alleviate propofol injection pain in patients undergoing painless abortion. Anxious patients require higher doses of esketamine to achieve effective analgesia. Individualizing esketamine dosing based on preoperative anxiety levels may enhance patient comfort and optimize pain management during anesthesia.
Authors
- Yanping Shen (ORCID: https://orcid.org/0000-0002-4546-850X)
- Biao Hu (ORCID: https://orcid.org/0000-0002-8972-291X)
- Liangguang Zhang (ORCID: https://orcid.org/0000-0002-3678-7197)
- Lijun Yin
- Yi Xia (ORCID: https://orcid.org/0000-0002-2838-2552)
Institutions
- Ningbo University (CN)
- Ningbo No.6 Hospital (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2024-12-01
- DOI
- https://doi.org/10.2147/dddt.s482019
- Citations
- 6
- Primary Topic
- Anesthesia and Pain Management
- Type
- article
- Field-Weighted Citation Impact
- 3.44
Funders
- Ningbo University