Magnetic-Powered Spora Lygodii Microrobots Loaded with Doxorubicin for Active and Targeted Therapy of Bladder Cancer
This study highlights the potential of integrating TCM with advanced microrobotics. The biocompatible Fe/DOX@SL microrobots leverage SL's therapeutic properties and fuel-free magnetic control to overcome challenges in bladder cancer treatment, such as poor drug retention and off-target toxicity. This novel platform represents a promising advancement in targeted cancer therapy. The innovative fusion of TCM and microrobotics introduces a potent, targeted therapeutic strategy for bladder cancer, paving the way for broader biomedical applications.
Authors
- Menghuan Tang (ORCID: https://orcid.org/0000-0002-1203-4473)
- Wen Yuan (ORCID: https://orcid.org/0000-0001-7328-1198)
- Zhaoqing Cong (ORCID: https://orcid.org/0000-0003-2737-7636)
- Song Wu (ORCID: https://orcid.org/0000-0003-3504-1630)
- Yang Jiao (ORCID: https://orcid.org/0000-0001-8753-8898)
- Qingxin Yang (ORCID: https://orcid.org/0000-0001-8547-0850)
- Tinghui Zhao
Institutions
- Shenzhen University (CN)
- Mianyang Third People's Hospital (CN)
- Mianyang Central Hospital (CN)
- Sichuan Mianyang 404 Hospital (CN)
- Shenzhen Luohu People's Hospital (CN)
- Shenzhen Third People’s Hospital (CN)
- University of California, Davis (US)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2024-12-01
- DOI
- https://doi.org/10.2147/dddt.s490652
- Citations
- 6
- Primary Topic
- Micro and Nano Robotics
- Type
- article
- Field-Weighted Citation Impact
- 1.87