Differentiating Glioma Recurrence and Pseudoprogression by APTw CEST MRI
Our study shows that APTw imaging can differentiate PD and PsPD. We identify previously undetectable imaging patterns during glioma recurrence, which include alterations within resection cavity associated with disease progression. Our work highlights the clinical potential of APTw imaging for glioma monitoring and further establishes it as an imaging biomarker in neuro-oncology.
Authors
- Nikolaus von Knebel Doeberitz (ORCID: https://orcid.org/0000-0002-8453-3220)
- Frank Winkler (ORCID: https://orcid.org/0000-0003-4892-6104)
- Lukas Bunse (ORCID: https://orcid.org/0000-0002-4490-7574)
- Martin Bendszus (ORCID: https://orcid.org/0000-0002-9094-6769)
- Wolfgang Wick
- Julius M. Kernbach (ORCID: https://orcid.org/0000-0002-0256-1923)
- Michael O. Breckwoldt (ORCID: https://orcid.org/0000-0002-9980-2390)
- Irada Pflüger
- Dániel Schwarz (ORCID: https://orcid.org/0000-0002-9017-8245)
- Michael Platten (ORCID: https://orcid.org/0000-0002-4746-887X)
- Johannes Ungermann (ORCID: https://orcid.org/0000-0002-7592-1299)
- Katharina Schregel (ORCID: https://orcid.org/0000-0003-4367-1667)
- Sabine Heiland (ORCID: https://orcid.org/0000-0002-2796-3451)
- Daniel Paech (ORCID: https://orcid.org/0000-0001-5755-6833)
- Franziska M. Ippen (ORCID: https://orcid.org/0000-0001-6870-1784)
- Kianush Karimian‐Jazi (ORCID: https://orcid.org/0000-0002-5550-0489)
- Hannah Fels-Palesandro
- Volker Sturm (ORCID: https://orcid.org/0000-0001-8681-9372)
- Noah Enbergs
- David Batra
- Evgeny Golubtsov
Institutions
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
Publication Details
- Journal
- Investigative Radiology
- Published
- 2024-12-07
- DOI
- https://doi.org/10.1097/rli.0000000000001145
- Citations
- 6
- Primary Topic
- Lanthanide and Transition Metal Complexes
- Type
- article
- Field-Weighted Citation Impact
- 0.70