Clinical utility of PCR compared to conventional culture and sensitivity testing for management of complicated urinary tract infections in adults: Part II.Evaluation of diagnostic concordance, discordant results, and antimicrobial selection efficacy
Our clinical utility study data suggests that PCR-guided management of cUTIs is overall superior to conventional C&S, offering several advantages. PCR has the potential to enhance patient care by enabling the early adoption of narrower antibiotic therapies, improving clinical outcomes, and ensuring the effective selection of antimicrobials. A PCR-guided management plan could be particularly beneficial in managing patients with cUTIs, addressing infections that are occasionally overlooked with current C&S-guided treatment protocols.
Authors
- Thomas K. Huard
- Michael Aberger
- Lauren Park (ORCID: https://orcid.org/0000-0002-3630-5506)
- Ben Wilson
- Moustafa Kardjadj (ORCID: https://orcid.org/0000-0002-9537-2274)
- DeAndre Derrick
- Khaled Ajib (ORCID: https://orcid.org/0000-0002-8776-1122)
- Frank L Spangler
- Shahram S. Gholami
- H. Goodwin
- Cheau Williams
Institutions
- Pacific University Oregon (US)
- University of Saint Joseph (US)
- Albany Technical College (US)
- American Association of Neurological Surgeons (US)
- Norman Regional Hospital (US)
- Augusta University Health (US)
- Canadian Association for Co-operative Education (CA)
- Soft Imaging LLC (United States) (US)
- Oklahoma Otolaryngology Associates (US)
- Saint Joseph Hospital (US)
- Regional Medical Center (US)
- ABS Consulting (United States) (US)
- Vårdcentralen Teleborg (SE)
Publication Details
- Journal
- Diagnostic Microbiology and Infectious Disease
- Published
- 2024-12-07
- DOI
- https://doi.org/10.1016/j.diagmicrobio.2024.116646
- Citations
- 6
- Primary Topic
- Urinary Tract Infections Management
- Type
- article
- Field-Weighted Citation Impact
- 2.32