How to protect the proximal bronchial tree during stereotactic radiotherapy of ultracentral lung tumors: Lessons from MR-guided treatment
Both intrafractional breathing motion and interfractional translations may impact doses to the PBT during SBRT of ULT. SMART protects the PBT from overdoses while maintaining high PTV coverage. Non-adaptive SBRT appears safe with advanced breathing motion management and PRV, but yields inferior PTV coverage.
Authors
- C. Katharina Renkamp
- Marietta Kirchner (ORCID: https://orcid.org/0000-0003-0294-2483)
- Sebastian Regnery (ORCID: https://orcid.org/0000-0002-6820-884X)
- Matthias Gückenberger (ORCID: https://orcid.org/0000-0002-7146-9071)
- Jan Meis (ORCID: https://orcid.org/0000-0001-5407-7220)
- Fabian Schlüter
- Sebastian Klüter (ORCID: https://orcid.org/0000-0003-3139-3444)
- Nicolaus Andratschke (ORCID: https://orcid.org/0000-0003-3647-5916)
- Carolin Rippke (ORCID: https://orcid.org/0000-0002-6519-928X)
- Juliane Hörner‐Rieber (ORCID: https://orcid.org/0000-0003-3911-4438)
- Jürgen Debus (ORCID: https://orcid.org/0000-0002-6411-4811)
- Fabian Weykamp (ORCID: https://orcid.org/0000-0003-1731-7090)
- Efthimios Katsigiannopulos (ORCID: https://orcid.org/0000-0001-5795-1999)
- Philipp Hoegen-Saßmannshausen
- Alexandra Balzer
- Hin Lau
- Sophia Albert
Institutions
- Zimmer Biomet (Netherlands) (NL)
- German Cancer Research Center (DE)
- University of Zurich (CH)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Düsseldorf University Hospital (DE)
- University Hospital of Zurich (CH)
- Heidelberger Institut für Radioonkologie (DE)
- National Center for Tumor Diseases (DE)
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- Clinical and Translational Radiation Oncology
- Published
- 2024-12-07
- DOI
- https://doi.org/10.1016/j.ctro.2024.100899
- Citations
- 2
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.84
Funders
- Pfizer
- AstraZeneca
- Varian Medical Systems
- Elekta
- Novocure
- Accuray
- ViewRay
- Deutsche Forschungsgemeinschaft
- Siemens Healthineers
- Army Research Office