Morphological and Mechanical Property Differences in Trapeziometacarpal Ligaments of Healthy and Osteoarthritic Female Joints
VLC morphological and mechanical properties deteriorate across progressively severe osteoarthritis classifications while the DRL and POL remain unchanged. The attenuated mechanical properties of VLCs in advanced-stage osteoarthritic TMCs can be explained by ligament degradation as evidenced by partial detachment and loss of mineral gradient at the metacarpal insertion.
Authors
- Hai Yao (ORCID: https://orcid.org/0000-0001-5130-5128)
- Shangping Wang (ORCID: https://orcid.org/0000-0003-0049-2212)
- Vincent D. Pellegrini (ORCID: https://orcid.org/0000-0001-7492-0684)
- Zhaoxu Meng (ORCID: https://orcid.org/0000-0002-3250-7696)
- Dane Daley (ORCID: https://orcid.org/0000-0002-9620-1311)
- Alexander M. Chiaramonti (ORCID: https://orcid.org/0000-0003-2487-7280)
- Lizzie Walker (ORCID: https://orcid.org/0009-0001-9980-6260)
- Yongren Wu (ORCID: https://orcid.org/0000-0002-5411-8528)
- Daniel Gordon
- Elizabeth H. Slate (ORCID: https://orcid.org/0000-0001-6372-5277)
Institutions
- Florida State University (US)
- Dartmouth–Hitchcock Medical Center (US)
- Medical University of South Carolina (US)
- Wake Forest University (US)
- Clemson University (US)
Publication Details
- Journal
- Annals of Biomedical Engineering
- Published
- 2024-12-07
- DOI
- https://doi.org/10.1007/s10439-024-03660-4
- Citations
- 2
- Primary Topic
- Orthopedic Surgery and Rehabilitation
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- Clemson University
- Medical University of South Carolina
- National Institutes of Health
- National Institute of General Medical Sciences