Surgical margin and other prognostic factors of invasive vulvar squamous cell carcinoma: A clinicopathological mono-center study
The surgical margin should be at least 1.0 cm away from the tumor edge. When the surgeons cannot ensure the negative margins, detecting surgical margins with rapid pathological examination may reduce the incidence of postoperative positive margins. FIGO stage III-IV, ILN metastases, and BMI ≥25 kg/m<sup>2</sup> are important adverse prognostic factors in VSCC patients. Cases with PNI may have poor prognosis. SCC-Ag might be a useful marker for predicting relapse.
Authors
- Yongyi Zhu
- Jiaqi Qiu
- Longyi Chen (ORCID: https://orcid.org/0000-0002-0464-3965)
- Min Zheng (ORCID: https://orcid.org/0000-0001-6159-9879)
- Zhimin Liu (ORCID: https://orcid.org/0009-0006-2159-6968)
- Yongwen Huang
- Heqing Zhao
- Nuerbiya Abula
- Yulin Wang (ORCID: https://orcid.org/0000-0002-3315-1927)
- Binghong Guo
Institutions
- Sun Yat-sen University (CN)
- Queensland University of Technology (AU)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Shantou University (CN)
- Cancer Hospital of Shantou University Medical College (CN)
- Sun Yat-sen University Cancer Center (CN)
- Hefei First People's Hospital (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e41042
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00