Low-Dose Acyclovir Reduces the Reactivation of Herpes Simplex and Varicella Zoster Viruses After Allogeneic Stem Cell Transplantation

Oral acyclovir 400 mg taken twice daily for prophylaxis in alloSCT recipients is both effective and well-tolerated. This lower-dose regimen effectively prevents HSV and VZV reactivation without compromising efficacy or patient safety.

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Publication Details

Journal
Cureus
Published
2024-12-07
DOI
https://doi.org/10.7759/cureus.75270
Primary Topic
Herpesvirus Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Low-Dose Acyclovir Reduces the Reactivation of Herpes Simplex and Varicella Zoster Viruses After Allogeneic Stem Cell Transplantation

Gina Patrus, Sorana G Ursu, Salman Fazal, Mohammad M. Alhousani
Cureus
Herpesvirus Infections and Treatments
article

Low-Dose Acyclovir Reduces the Reactivation of Herpes Simplex and Varicella Zoster Viruses After Allogeneic Stem Cell Transplantation

Gina Patrus, Sorana G Ursu, Salman Fazal, Mohammad M. Alhousani
article en

Abstract

Oral acyclovir 400 mg taken twice daily for prophylaxis in alloSCT recipients is both effective and well-tolerated. This lower-dose regimen effectively prevents HSV and VZV reactivation without compromising efficacy or patient safety.

CureusVol. 16(12)
Allegheny Health Network (US)
Zero hunger
Openalex Percentile: Top 66%
Herpesvirus Infections and Treatments
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Low-Dose Acyclovir Reduces the Reactivation of Herpes Simplex and Varicella Zoster Viruses After Allogeneic Stem Cell Transplantation — Gina Patrus, Sorana G Ursu, et al. · Cureus (2024) | TGRS Research Map | TGRS