Blinatumomab in Standard-Risk B-Cell Acute Lymphoblastic Leukemia in Children

Adding blinatumomab to combination chemotherapy in patients with newly diagnosed childhood standard-risk B-cell ALL of average or higher risk of relapse significantly improved disease-free survival. (Funded by the National Institutes of Health and others; AALL1731 ClinicalTrials.gov number, NCT03914625.).

Authors

Institutions

Publication Details

Journal
New England Journal of Medicine
Published
2024-12-07
DOI
https://doi.org/10.1056/nejmoa2411680
Citations
144
Primary Topic
Acute Lymphoblastic Leukemia research
Type
article
Field-Weighted Citation Impact
78.18

Funders

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article

Blinatumomab in Standard-Risk B-Cell Acute Lymphoblastic Leukemia in Children

Susan J. Conway, Karen R. Rabin, Mignon L. Loh, Brent Lee Wood et al.
144 citations
New England Journal of Medicine
Acute Lymphoblastic Leukemia research
78.18
article

Blinatumomab in Standard-Risk B-Cell Acute Lymphoblastic Leukemia in Children

Susan J. Conway, Karen R. Rabin, Mignon L. Loh, Brent Lee Wood, Holly R. Kubaney, Ilan Kirsch, Stephen P. Hunger, Gerhard Zugmaier, Mary Shago, Elizabeth A. Raetz, John A. Kairalla, Elizabeth M. Wagner, David T. Teachey, Anne Angiolillo, Sarah W. Alexander, Tamara P. Miller, Rachel E. Rau, Lia Gore, Olga Militano, Naomi Joan Winick, Yvonne Moyer, Amanda M. Li, Jennifer L. McNeer, Shalini C. Reshmi, Maureen M. O’Brien, Andrew J. Carroll, Sumit Gupta, Faraz Zaman, Sue Zupanec, Meenakshi Devidas, Cindy Wang, Maki Okada, Tara Haworth-Wright
article en
144 citations

Abstract

Adding blinatumomab to combination chemotherapy in patients with newly diagnosed childhood standard-risk B-cell ALL of average or higher risk of relapse significantly improved disease-free survival. (Funded by the National Institutes of Health and others; AALL1731 ClinicalTrials.gov number, NCT03914625.).

New England Journal of MedicineVol. 392(9)
Seattle Children's Hospital (US), St. Jude Children's Research Hospital (US), Nationwide Children's Hospital (US), Amgen (United States) (US), Primary Children's Hospital (US), Children's Hospital of Philadelphia (US), Children's Hospital of Los Angeles (US), Emory University (US), University of Toronto (CA), University of Florida Health (US), Toronto General Hospital (CA), University of Alabama at Birmingham (US), NYU Langone Health (US), Fred Hutch Cancer Center (US), Children's Hospital Colorado (US), Southwestern Medical Center (US), Dell Children's Medical Center of Central Texas (US), Adaptive Biotechnologies (United States) (US), Center for Cancer and Blood Disorders (US), Miller Children's & Women's Hospital (US), Amgen (Germany) (DE), Children's Oncology Group (US), Servier (France) (FR), Children's Cancer Center (US), BC Children's Hospital (CA), University of Pennsylvania (US), The University of Texas Southwestern Medical Center (US), University of Colorado Denver (US)
St. Baldrick's Foundation, National Institutes of Health, National Cancer Institute
Openalex Percentile: Top 0%
Acute Lymphoblastic Leukemia research
78.18
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