Effects of PGK1 on immunoinfiltration by integrated single-cell and bulk RNA-sequencing analysis in sepsis
This study concluded that PGK1 served as a novel diagnostic biomarker for sepsis, with potential implications for prognosis and immune regulation. The significant upregulation of PGK1 in sepsis patients and its association with immune-related pathways and cell types highlight its potential role in the pathogenesis of sepsis.
Authors
- Yaoliang Zhou
- Haiqi Wu
- Chun Tang (ORCID: https://orcid.org/0000-0001-6590-1617)
- Yide Li (ORCID: https://orcid.org/0000-0003-4737-7975)
- Yingyu Jiang (ORCID: https://orcid.org/0000-0003-3286-2150)
- Kongyang Ma (ORCID: https://orcid.org/0000-0002-9739-7686)
- Zhihua Zheng (ORCID: https://orcid.org/0000-0002-5222-3930)
- Yu Liu (ORCID: https://orcid.org/0000-0001-8359-6732)
- Lei Lei (ORCID: https://orcid.org/0000-0003-0987-5092)
- Weijie Li (ORCID: https://orcid.org/0000-0002-3452-3745)
- Xiaoying Zhang (ORCID: https://orcid.org/0000-0002-0055-7322)
- Mingcheng Huang (ORCID: https://orcid.org/0000-0002-2807-1973)
Institutions
- Sun Yat-sen University (CN)
- The Seventh Affiliated Hospital of Sun Yat-sen University (CN)
- Hezhou University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-12-06
- DOI
- https://doi.org/10.3389/fimmu.2024.1449975
- Citations
- 3
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.72
Funders
- Basic and Applied Basic Research Foundation of Guangdong Province