Case report: A rare case of intragastric metastasis after liver transplantation for liver cancer

A 13-year-old boy was admitted to Xiang'an Hospital of Xiamen University due to HBV-related liver cancer. Intrahepatic metastasis was considered to occur by CT scan. A gastroscope revealed esophagogastric variceal bleeding, and later, the patient underwent a successful liver transplantation. Fourteen months posttransplant, chest CT indicated lung metastasis, and the patient underwent thoracoscopic radical resection of lung cancer. Twenty-one months posttransplant, gastroscopy revealed a gastric fundus tumor growing into the gastric cavity. Proximal gastrectomy was performed, and pathology indicated moderately to poorly differentiated carcinoma without invasion of serosa, suggesting the first study to report HCC metastasis to the stomach lumen without invasion of serosa after LT. Currently, the alpha-fetoprotein (AFP) level of the patient has dropped below normal.

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Publication Details

Journal
Frontiers in Oncology
Published
2024-12-06
DOI
https://doi.org/10.3389/fonc.2024.1495517
Primary Topic
Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Case report: A rare case of intragastric metastasis after liver transplantation for liver cancer

Guimei Wang, Wenbin An, Zhihai Peng, Yuzheng Xue et al.
Frontiers in Oncology
Cancer Diagnosis and Treatment
article

Case report: A rare case of intragastric metastasis after liver transplantation for liver cancer

Guimei Wang, Wenbin An, Zhihai Peng, Yuzheng Xue, Zhaojie Su, Baojie Shi, Hao Li, Jie Wang, Yunyun Qian, Jianfa Zhong
article en

Abstract

A 13-year-old boy was admitted to Xiang'an Hospital of Xiamen University due to HBV-related liver cancer. Intrahepatic metastasis was considered to occur by CT scan. A gastroscope revealed esophagogastric variceal bleeding, and later, the patient underwent a successful liver transplantation. Fourteen months posttransplant, chest CT indicated lung metastasis, and the patient underwent thoracoscopic radical resection of lung cancer. Twenty-one months posttransplant, gastroscopy revealed a gastric fundus tumor growing into the gastric cavity. Proximal gastrectomy was performed, and pathology indicated moderately to poorly differentiated carcinoma without invasion of serosa, suggesting the first study to report HCC metastasis to the stomach lumen without invasion of serosa after LT. Currently, the alpha-fetoprotein (AFP) level of the patient has dropped below normal.

Frontiers in OncologyVol. 14
Xiamen University (CN), Fuzhou Pulmonary Hospital of Fujian (CN)
Science Fund for Distinguished Young Scholars of Fujian Province
Good health and well-being
Openalex Percentile: Top 61%
Cancer Diagnosis and Treatment
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Case report: A rare case of intragastric metastasis after liver transplantation for liver cancer — Guimei Wang, Wenbin An, et al. · Frontiers in Oncology (2024) | TGRS Research Map | TGRS