Time-dependent variation in immunoparalysis biomarkers among patients with sepsis and critical illness
These findings suggest the need for more nuanced immune monitoring approaches beyond the traditional 'sepsis' versus 'non-sepsis' classifications in critically ill patients. Additionally, they provide further evidence of a potential window for targeted immunotherapy in the first weeks of critical illness.
Authors
- Anthony Bonavia (ORCID: https://orcid.org/0000-0001-9596-001X)
- Erik Lehman (ORCID: https://orcid.org/0000-0003-3642-0632)
- Abigail Samuelsen
- Parker Burrows
Institutions
- Pennsylvania State University (US)
- Penn State Milton S. Hershey Medical Center (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-12-06
- DOI
- https://doi.org/10.3389/fimmu.2024.1498974
- Citations
- 9
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.48
Funders
- University of Pennsylvania
- Pennsylvania State University
- Penn State College of Medicine
- National Institute of General Medical Sciences