Lysophosphatidylcholine 14:0 Alleviates Lipopolysaccharide-Induced Acute Lung Injury via Protecting Alveolar Epithelial Barrier by Activation of Nrf2/HO-1 Pathway
This study first demonstrated that LPC14:0 mitigated LPS-induced ALI and the destruction of tight junctions, at least in part through up-regulation of the Nrf2/HO-1 pathway.
Authors
- Li-Wen Zhou
- Sijuan Zou (ORCID: https://orcid.org/0000-0002-6501-3983)
- Lijing Xia
- Pengcheng Lin (ORCID: https://orcid.org/0000-0002-0697-0011)
- Shixin Su (ORCID: https://orcid.org/0000-0002-5334-2827)
- Yuping Li (ORCID: https://orcid.org/0000-0002-5833-931X)
- Kai Li (ORCID: https://orcid.org/0000-0001-5050-0175)
- Xiling Liu (ORCID: https://orcid.org/0000-0003-1318-6150)
- Xiong Lei
- Ruihua Yang (ORCID: https://orcid.org/0000-0001-8439-178X)
Institutions
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2024-12-01
- DOI
- https://doi.org/10.2147/jir.s495227
- Citations
- 6
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 2.51