Impaired Basal Forebrain Cholinergic Neuron <scp>GDNF</scp> Signaling Contributes to Perioperative Sleep Deprivation–Induced Chronicity of Postsurgical Pain in Mice Through Regulating Cholinergic Neuronal Activity, Apoptosis, and Autophagy
Perioperative sleep deprivation promotes chronicity of postsurgical pain possibly through decreasing basal forebrain GDNF signaling and causing cholinergic neuronal apoptosis and autophagy dysfunction.
Authors
- Fengsheng Li (ORCID: https://orcid.org/0000-0001-5051-9669)
- Shi‐Nan Wei
- Si‐Nian Wang
- Yan Lü (ORCID: https://orcid.org/0000-0001-5353-4362)
- Xiuying Wang (ORCID: https://orcid.org/0000-0001-7160-5929)
- Bo Cheng (ORCID: https://orcid.org/0000-0003-1916-0410)
- Wei Qiang Wang (ORCID: https://orcid.org/0000-0002-1430-1360)
- Han Zhang (ORCID: https://orcid.org/0000-0002-0166-1973)
- Dong Wang (ORCID: https://orcid.org/0009-0006-1137-021X)
- Zhi‐Chen Lang
- Lu Zhang (ORCID: https://orcid.org/0009-0006-8207-5824)
Institutions
- Zhengzhou Central Hospital (CN)
- Central Hospital of Zibo (CN)
- Jinzhou Medical University (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1111/cns.70147
- Citations
- 4
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.31
Funders
- National Natural Science Foundation of China