P-95 SARCOPENIA: RISK FACTOR FOR MORTALITY IN CIRRHOTIC PATIENTS ON WAITING LIST FOR LIVER TRANSPLANTATION IN A REFERENCE CENTER, COLOMBIA

No Sarcopenia is an independent predictor of mortality in patients with chronic liver disease pre- and post-transplant. Measurement of muscle strength by dynamometry can serve as a surrogate marker of frailty in patients with chronic liver disease, especially in those in whom it is not possible to assess sarcopenia through imaging. To determine the association between sarcopenia, complications of cirrhosis and mortality in cirrhotic patients on the waiting list for liver transplant in a liver transplant reference center in Colombia. Methods : An observational, analytical and retrospective study was carried out with a cohort of patients with cirrhosis on the waiting list for liver transplant between 2020 and 2022, in a liver transplant reference center in Colombia. We included 310 patients with a diagnosis of cirrhosis who were on the liver transplant waiting list and had dynamometry and anthropometry records to calculate the SARC-F index. A bivariate analysis was carried out which shows that a high score in CHILDA, MELD, ICU stay, complications such as SBP, dynamometry measurement and sarcopenia generate an estimate of significant association, taking into account a p <0.05. Subsequently, a multinomial logistic regression model was carried out, chronic kidney disease and sarcopenia stand out as influential factors in mortality with P <0.05. Sarcopenia and chronic kidney disease are factors that have a significant association with higher mortality.