Sequence-selective pulldown of recognition-encoded melamine oligomers using covalent capture on a solid support
The covalent capture of recognition-encoded melamine oligomers (REMO) with a target attached to a solid support was investigated. Sequence-selective pulldown of complementary oligomers was observed when the target was challenged with a randomised library of oligomers. The approach provides an affinity selection method for the discovery of functional REMO sequences.
Authors
- Luis Escobar (ORCID: https://orcid.org/0000-0003-0392-8245)
- Daniel T. Sun (ORCID: https://orcid.org/0009-0005-7140-4998)
- Christopher A. Hunter (ORCID: https://orcid.org/0000-0002-5182-1859)
- Mohit Dhiman (ORCID: https://orcid.org/0009-0001-5839-719X)
Institutions
- University of Cambridge (GB)
Publication Details
- Journal
- Chemical Communications
- Published
- 2024-12-06
- DOI
- https://doi.org/10.1039/d4cc06018k
- Citations
- 1
- Primary Topic
- Advanced biosensing and bioanalysis techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- European Research Council