Childhood adversity and late‐life cognitive and brain health in a diverse cohort
We developed measurement models to capture childhood adversity in a diverse cohort. Childhood adversity was associated with a slightly faster verbal memory decline. We examined childhood adversity's effect on structural MRI and amyloid PET measures. Higher childhood adversity was associated with larger temporal lobe volumes.
Authors
- Evan Fletcher (ORCID: https://orcid.org/0000-0002-9761-3131)
- M. Maria Glymour (ORCID: https://orcid.org/0000-0001-9644-3081)
- Elizabeth Rose Mayeda (ORCID: https://orcid.org/0000-0002-6326-0163)
- Lisa L. Barnes (ORCID: https://orcid.org/0000-0002-0072-9817)
- Karestan C. Koenen (ORCID: https://orcid.org/0000-0003-2978-7655)
- Lindsay C. Kobayashi (ORCID: https://orcid.org/0000-0003-2725-3107)
- Joseph Fong
- Dan Mungas (ORCID: https://orcid.org/0000-0003-2035-7085)
- Eleanor Hayes‐Larson (ORCID: https://orcid.org/0000-0001-8299-2389)
- Rachel A. Whitmer (ORCID: https://orcid.org/0009-0006-9511-6138)
- Natalie M. Gradwohl
- Paola Gilsanz (ORCID: https://orcid.org/0000-0002-7635-381X)
- Charles DeCarli
Institutions
- Boston University (US)
- University of Southern California (US)
- Kaiser Permanente (US)
- Harvard University (US)
- University of California, Los Angeles (US)
- University of Michigan (US)
- Rush University (US)
- University of California, Davis (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-06
- DOI
- https://doi.org/10.1002/alz.14388
- Citations
- 8
- Primary Topic
- Child Abuse and Trauma
- Type
- article
- Field-Weighted Citation Impact
- 5.11
Funders
- National Institutes of Health