Radiologically Negative Colorectal Diaphragmatic Metastasis Mimicking Liver Lesion

Colorectal Diaphragmatic Metastasis Mimicking Liver LesionFu, Jin, and Chen were resected, and histopathologic examination confirmed diaphragmatic metastasis composed of adenocarcinoma cells with central necrosis (Figure, D), along with satellite foci of adenocarcinoma.The patient recovered well and received postoperative adjuvant therapy, with no new metastatic lesions detected.The liver is the most frequent metastatic site for colorectal cancer, while peritoneal metastases rank third (1).The origin of metastatic lesions can usually be determined using enhanced CT or MRI scans (2). 18F-FDG PET/CT and 68 Ga-FAPI PET/CT demonstrated over 90% sensitivity in detecting metastatic lesions (3,4).However, false negatives can arise from minute lesions or decreased activity of tumor cells.The coincidental