Variation of Bruch's membrane opening in response to intraocular pressure change during scleral lens wear, in a population with keratoconus

BMO-MRW became significantly thinner after 6 h of scleral lens wear compared with measurements without lenses. These variations may be associated with a rise in IOP during lens wear. Close monitoring for optic head changes should be carried out for patients at risk. These results should be compared with future longer-term studies including a larger cohort of patients.