An updated AL-base reveals ranked enrichment of immunoglobulin light chain variable genes in AL amyloidosis

Rarely-observed light chain variable genes may carry a high risk of AL amyloidosis. New approaches are needed to define sequence-associated risk factors for AL amyloidosis. AL-Base is a foundational resource for such studies.

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Publication Details

Journal
Amyloid
Published
2024-12-06
DOI
https://doi.org/10.1080/13506129.2024.2434899
Citations
14
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
Field-Weighted Citation Impact
3.27
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article

An updated AL-base reveals ranked enrichment of immunoglobulin light chain variable genes in AL amyloidosis

Brian Spencer, Tatiana Prokaeva, Vaishali Sanchorawala, Axin Hua et al.
14 citations
Amyloid
Amyloidosis: Diagnosis, Treatment, Outcomes
3.27
article

An updated AL-base reveals ranked enrichment of immunoglobulin light chain variable genes in AL amyloidosis

Brian Spencer, Tatiana Prokaeva, Vaishali Sanchorawala, Axin Hua, Gareth J. Morgan, Sherry Wong, Yun Shen, Allison Nau, Matthew J. Bullard
article en
14 citations

Abstract

Rarely-observed light chain variable genes may carry a high risk of AL amyloidosis. New approaches are needed to define sequence-associated risk factors for AL amyloidosis. AL-Base is a foundational resource for such studies.

AmyloidVol. 32(2)
Boston University (US), Boston Medical Center (US), Amyloidosis Foundation (US), University Research Co (United States) (US)
Zero hunger
Openalex Percentile: Top 7%
Amyloidosis: Diagnosis, Treatment, Outcomes
3.27
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