Circulating Stress Hormones, Brain Health, and Cognition in Healthy Older Adults: Cross-Sectional Findings and Sex Differences in Age-Well
The current study demonstrates the involvement of circulating stress hormones, particularly epinephrine and cortisol, in greater resilience or vulnerability of brain health and cognitive indicators of susceptibility to AD in older adults. The identification of sex-specific patterns in these associations may inform the development of more effective and tailored interventions.
Authors
- Gaël Chételat (ORCID: https://orcid.org/0000-0002-4889-7932)
- Natalie L. Marchant (ORCID: https://orcid.org/0000-0003-0669-6910)
- Géraldine Poisnel (ORCID: https://orcid.org/0000-0001-7943-1281)
- Marion Delarue (ORCID: https://orcid.org/0000-0002-8934-8649)
- Olga Klimecki (ORCID: https://orcid.org/0000-0003-0757-7761)
- Florence Mézenge
- Miranka Wirth (ORCID: https://orcid.org/0000-0002-0725-7314)
- Brigitte Landeau (ORCID: https://orcid.org/0000-0002-0814-3714)
- Steven Hass (ORCID: https://orcid.org/0000-0002-1686-030X)
- Anne Chocat
- Maxie Liebscher (ORCID: https://orcid.org/0009-0000-7625-5673)
- Oriane Hébert
- Anne‐Laure Turpin
- Silke White
Institutions
- Inserm (FR)
- German Center for Neurodegenerative Diseases (DE)
- Normandie Université (FR)
- Cyceron (FR)
- University College London (GB)
- Technische Universität Dresden (DE)
- Université de Caen Normandie (FR)
Publication Details
- Journal
- Biological Psychiatry Global Open Science
- Published
- 2024-12-06
- DOI
- https://doi.org/10.1016/j.bpsgos.2024.100431
- Citations
- 1
- Primary Topic
- Stress Responses and Cortisol
- Type
- article
- Field-Weighted Citation Impact
- 0.29
Funders
- European Commission
- Institut National de la Santé et de la Recherche Médicale
- Région Normandie