Association Between Serum Antinuclear Antibody and Polycystic Ovarian Syndrome in Reproductive Women Aged 18 to 35 Years: A Quest for an Autoimmune Marker

There was no statistically significant association between ANA positivity and PCOS, but we found an increased prevalence of ANA in the PCOS group as compared to the non-PCOS group.Though our study did not find a significant association between ANA positivity and modified Ferriman Gallwey score, serum testosterone levels, and HOMA-IR levels, we found a significant increase in anti-TPO levels in ANA-positive PCOS women. We conclude that the increased prevalence of ANA positivity in PCOS could be an indicator of autoimmunity.