A Randomized Trial Comparing Inhaled Insulin Plus Basal Insulin Versus Usual Care in Adults With Type 1 Diabetes
In adults with type 1 diabetes, HbA1c after 17 weeks with a regimen of TI and degludec was noninferior to UC, which consisted predominately of either AID or MDI. TI should be considered an option for people with type 1 diabetes, particularly those who are motivated to further reduce postprandial hyperglycemia.
Authors
- Andrea D. Coviello (ORCID: https://orcid.org/0000-0003-0244-9787)
- Martin Chase Marak (ORCID: https://orcid.org/0009-0008-0908-7911)
- Jamie Hyatt
- Carol J. Levy (ORCID: https://orcid.org/0000-0002-3492-2578)
- Thomas Blevins (ORCID: https://orcid.org/0000-0003-3746-9606)
- Bruce W. Bode (ORCID: https://orcid.org/0000-0002-9998-055X)
- David Pickering
- Karla Fulghum
- Jonathan G. Ownby
- Philip Raskin
- Halis Kaan Aktürk (ORCID: https://orcid.org/0000-0003-4518-5179)
- Shilton Dhaver (ORCID: https://orcid.org/0000-0002-5281-6728)
- Alexander Kass
- Jesica D. Baran
- E E Mason (ORCID: https://orcid.org/0000-0002-9577-2286)
- Anuj Bhargava (ORCID: https://orcid.org/0000-0002-5961-6171)
- Irl B. Hirsch (ORCID: https://orcid.org/0000-0003-1675-8417)
- Tina Copple
- Corey Reid
- Richard M. Bergenstal (ORCID: https://orcid.org/0000-0002-9050-5584)
- Grenye O’Malley (ORCID: https://orcid.org/0000-0001-7940-2624)
- Shafaq Rizvi
- John B. Buse (ORCID: https://orcid.org/0000-0002-9723-3876)
- Joseph H. Johnson
- Chris McCarthy (ORCID: https://orcid.org/0000-0002-5587-8203)
- Kristin Castorino (ORCID: https://orcid.org/0000-0001-6386-9203)
- Astrid Atakov-Castillo (ORCID: https://orcid.org/0000-0001-9505-8528)
- Donna Desjardins
- Adriana Ruiz
- Camilla Levister
- Kevin B. Kaiserman (ORCID: https://orcid.org/0000-0002-3215-4317)
- Mark S. Kipnes
- Christopher Jacobson (ORCID: https://orcid.org/0009-0004-6492-6280)
- Devin Steenkamp (ORCID: https://orcid.org/0000-0001-7132-3657)
- E. N. Dolzhenko
- Laura Young (ORCID: https://orcid.org/0000-0002-5803-0419)
- Adham Mottalib (ORCID: https://orcid.org/0000-0002-8573-6329)
- Valerie Espinosa
- Terri Ryan
- Katrina J. Ruedy
- Tahereh Ghorbani
- Yogish C. Kudva (ORCID: https://orcid.org/0000-0003-0285-6622)
- Jamie Diner
- Howard Wolpert (ORCID: https://orcid.org/0000-0001-9771-6344)
- Jelena Kravarusic
- Jesica Baran
- Anastasios Manessis (ORCID: https://orcid.org/0000-0002-5473-0573)
- Olivia Johnson (ORCID: https://orcid.org/0000-0002-7803-0862)
- Kevin Codorniz
- Grazia Aleppo (ORCID: https://orcid.org/0000-0003-1644-5947)
- Sarah Frey
- Ashley Thorsell
- Loida Nguyen
- Zehra Haider
- Maria Patruno
- Johanna Ulloa
- Ruth S. Weinstock (ORCID: https://orcid.org/0000-0001-5859-5666)
- Roy W. Beck (ORCID: https://orcid.org/0000-0002-5194-8446)
- Andrew Ahmann (ORCID: https://orcid.org/0000-0002-4544-5404)
- Klara R. Klein (ORCID: https://orcid.org/0000-0002-5894-9054)
- Christie Beatson (ORCID: https://orcid.org/0000-0003-4414-5933)
- Patali Mandava
- Suzan Bzdick
- Rosanna Holod
- Amna Salhin
- Osama Hamdy (ORCID: https://orcid.org/0000-0002-1919-0268)
- Tareq Salah (ORCID: https://orcid.org/0000-0002-3978-6384)
- Paige Miller (ORCID: https://orcid.org/0009-0007-2327-5823)
- Marwa Al Badri
- Jennifer Pleitez
- Baomei Shao
- Scott Lee (ORCID: https://orcid.org/0000-0002-2913-3777)
- Ravinder Jeet Kaur (ORCID: https://orcid.org/0000-0001-6445-2776)
- Christine Burke
- Peter Calhoun (ORCID: https://orcid.org/0000-0003-3688-578X)
- Sue A. Brown (ORCID: https://orcid.org/0000-0002-8658-6270)
- Keta Pandit
- Ana Stewart
- Maggie Shuirman
- Nnenna Mba-Oduwusi
- Ashleigh Fults
- Denisa Tamarez
- Christine Langel
- Daine Livingood
- Evelyn Fronczyk
- Lorcan McKillop
- Olivia Watt
- Maritza Martinez-Arredondo
- Joey Sylvan
- Lynn Badgett
- Amanda Maxson
- Brittney Migliozzi
- Dana Cruse
- Jennifer Perez
- A. Bohr
- Kasey Coyne
- Brandon Cobb
- Cassandra Donahue
- Asya Sullivan
- Rosa Pritchard
- Chloe Armstrong
- Stefanie Herrmann
- Sarah Borgman
- Deanna Gabrielson
- Luis Casaubon
- Aslihan Ipek
- Nashia Stephens
- Stephanie Beltran
- Cristina Haight
- Corey Kurek
- Christian Cordero
- Quang T. Nguyen
- Lin Jordan
- Shannon Bauman
Institutions
- Boston University (US)
- Northwestern University (US)
- University of North Carolina at Chapel Hill (US)
- Boston Medical Center (US)
- Midwestern University (US)
- Joslin Diabetes Center (US)
- University of Washington (US)
- SUNY Upstate Medical University (US)
- Loma Linda University (US)
- West Virginia University at Parkersburg (US)
- Sansum Diabetes Research Institute (US)
- Atlanta Diabetes Associates (US)
- Diabetes & Glandular Disease Clinic (US)
- Mayo Clinic in Arizona (US)
- Texas Diabetes & Endocrinology (US)
- Jaeb Center for Health Research (US)
- Iowa Diabetes and Endocrinology Research Center (US)
- The University of Texas Southwestern Medical Center (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Diabetes Care
- Published
- 2024-12-06
- DOI
- https://doi.org/10.2337/dc24-1832
- Citations
- 20
- Primary Topic
- Diabetes Management and Research
- Type
- article
- Field-Weighted Citation Impact
- 7.15
Funders
- Amgen
- Eli Lilly and Company
- Pfizer
- AstraZeneca
- Sanofi
- Gilead Sciences
- Northwestern University
- Vertex Pharmaceuticals
- Ionis Pharmaceuticals
- Bigfoot Biomedical
- Insulet Corporation
- MannKind Corporation
- Dexcom
- Kowa Company
- Jaeb Center for Health Research
- Tandem Diabetes Care
- Moderna
- Novo Nordisk
- Abbott Diabetes Care
- National Institute of Diabetes and Digestive and Kidney Diseases
- Janssen Pharmaceuticals